48 MG CA
50 MG CA
52 MG CA
54 ACT MG CA
59 CA
82 PEG CA
84 CA
86 CA
88 ACT MG CA
93 CA
117 CA
119 CA
121 CA
123 CA
128 MPD CA
151 CA
153 CA
155 MPD GOL CA
165 CA
170 MPD CA

Best hits are calmodulin like domains, interpro prediction is calcium binding. Accept all CA contacts(?)

Segments 48-59 and 117-128 perfectly match the Prosite pattern for EF-hand domains. Region 82-93 seems fairly conserved and could reasonably form an additional Ef-hand motif. Residues His151, Ile153, Lys155, Lys165 and Glu170 are unlikely to form a typical calcium binding site, and only Glu170 looks somewhat conserved.

PFRMAT FN
TARGET T0521
AUTHOR 7656-5034-1890
REMARK Sequence consensus of contacts between homologous structures and ligands
METHOD pGenTHREADER and PDBSum and CSA data mining.
MODEL 1
Binding site: 48, 50, 52, 54, 59, 82, 84, 86, 88, 93, 117, 119, 121, 123, 128, 170
END

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« This page (revision-1) was last changed on 26-May-2010 13:15 by UnknownAuthor