Domenico:
Potential kinase. unfortunately we only can make use of one medium template - code 2pgnA0 - complexed with FAD to drive our prediction. Target positions matching amino acids contacting FAD in the template and achieving a conservation score of at least 7: Gly68, Met69, Pro106, Pro141, His144 and Phe158. This looks to underpredict the ATP binding site. Maybe we could also include residues with conservation score of 6? they are Gly107 and Gly142.

PFRMAT FN
TARGET T0628
AUTHOR 7656-5034-1890
REMARK Sequence consensus of contacts between homologous structures and ligands
METHOD pGenTHREADER and PDBSum and CSA data mining.
MODEL 1
Binding site: 68, 69, 106, 107, 141, 142, 144, 158
END

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« This page (revision-1) was last changed on 27-Jul-2010 13:07 by UnknownAuthor